Comparison of analgesic efficacy of ultrasound-guided Quadratus Lumborum block versus Erector Spinae plane block in children undergoing elective laparoscopic pyeloplasty – A randomized, double-blinded, controlled study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Comparison of post operative analgesia over the first 24 hours after ultrasound-guided Quadratus Lumborum block versus Erector Spinae plane block
研究概览
简要总结
AIM: To compare the analgesic efficacy of ultrasound-guided Quadratus Lumborum block versus Erector Spinae plane block in children undergoing elective laparoscopic pyeloplasty
Methods: Study will be conducted after ethical approval in paediatric patients (age 2-15 year) of either sex belonging to ASA 1 or 2 class undergoing laparoscopic pyeloplasty for pelviuretric junction obstruction. Patients (total 100) will be randomly assigned into two groups:
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Group Q: receiving anterior QL block under all aseptic precautions in a lateral position (side to be blocked upward) with 0.5 ml/kg of 0.2% ropivacaine.
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Group E: receiving the ESP block at T10 level under all aseptic precautions placing patients in a lateral position (side to be blocked upward) with 0.5 ml/kg of 0.2% ropivacaine.
Postoperative pain will be assessed at specified intervals using the Modified Objective Pain Score (MOPS). Total number of rescue analgesia given (Inj Tramadol 1.5 mg/kg) will be noted. Any side effects like motor block, nausea, vomiting and urinary retention will also be noted.
Objectives: Primary- MOPS score at 12 hours
Secondary- 1. MOPS score at 2, 4,8,12, 24 and 48 hrs
2. Need of rescue analgesia in no. of dosage (Tramadol 1.5 mg/kg) in the postoperative period.
3. Motor weakness
4. Parent satisfaction scale under 4-point Likert scale
5. Time to discharge
Study Period: 1 year
研究设计
- 研究类型
- Interventional
- 分配方式
- Computer generated randomization
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 2.00 Year(s) 至 15.00 Year(s)（—）
- 性别
- All
入选标准
- •Age group between 2 -15 years of either sex 2) Patients having Pelviureteric junction obstruction 3) Patients belonging to American Society of Anaesthesiologists physical status I and II.
排除标准
- •Parent/legal guardian refusal.
- •Age less than 2 years or more than 15 years 3) Children with, coagulopathy/sepsis.
- •Obesity(body mass index more than 30 kg per square metre) 5) Those who were converted to open 6) Those who couldn’t be extubated at end of surgery 7) Major intraoperative adverse events.
结局指标
主要结局
Comparison of post operative analgesia over the first 24 hours after ultrasound-guided Quadratus Lumborum block versus Erector Spinae plane block
时间窗: MOPS score at 0,1,2,3, 4,8,12,16, 20, 24 hours after the completion of surgery.
次要结局
- MOPS score(2, 4,8,12, 24 and 48 hrs)
- Need of rescue analgesia in no. of dosage (Tramadol 1.5 mg/kg) in the postoperative period.
- Parent satisfaction scale under 4-point Likert scale
- Motor weakness
- Time to discharge