Relief of pain after kidney stone surgery: A study comparing two types of nerve blocks using ropivacaine

Not yet recruiting

• Conditions: Calculus of ureter,

• Registration Number: CTRI/2025/06/089068
• Lead Sponsor: Medical College Kolkata

Brief Summary

TITLE - COMPARISON OF ANALGESIC EFFICACY BETWEEN ULTRASOUND-GUIDEDPARAVERTEBRAL BLOCK AND ERECTOR SPINAEPLANE BLOCK USING ROPIVACAINE  AFTER PERCUTANEOUSNEPHROLITHOTOMY IN MEDICAL COLLEGE, KOLKATA

Acute postoperative pain after percutaneousnephrolithotomy surgery often hinders early recovery and may also lead tochronic post surgical pain, which lowers quality of life. Paravertebral blockis an excellent choice for postoperative analgesia. The erector spinae planeblock is also emerging as an effectivealternative.

Ropivacaine is a long-acting amide localanaesthetic. It exhibits a similar mechanism of action to other localanaesthetics in that it reversibly inhibits sodium ion influx in nerve fibers. Ropivacaine has some unique properties.Ropivacaine is less lipophilic than other local anaesthetics and is less likelyto penetrate large myelinated motor fibers. It, therefore, selectively acts onthe nociceptive

A, B, and Cfibers over the AB (motor) fibers resulting in a relatively reduced motorblockade. Thus, ropivacaine has a greater degree of motor sensorydifferentiation, which can be useful in this scenario where motor blockade isundesirable. Ropivacaine  hassignificantly less cardiotoxicity and neurotoxicity.  The aim of this study is tocompare the analgesic efficacy of paravertebral block anderector spinae plane block using Ropivacainein preventing acute post surgical pain following Percutaneous nephrolithotomy.

Detailed Description

Not available

Study Timeline

• Study Start: 2025-01-08
• Last Update Posted: 2025-06-17

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Patients posted for unilateral percutaneous nephrolithotomy under general anesthesia.
• ASA Grade 1 and 2 patients.
• Body weight between 50 kg to 70 kg.

Exclusion Criteria

• Patient refused to give consent.
• Patient with contraindications for local anesthesia.
• Patient with severe psychiatric disorders.
• Renal stones which required more than one puncture, supra costal puncture.
• Intraoperative excessive bleeding.
• Obesity (BMI more than 30).Patient with history of chronic pain and drug abuse.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Comparison of Analgesic Efficacy Between Ultrasound-Guided Paravertebral Block and Erector Spinae Plane Block Using Ropivacaine After Percutaneous Nephrolithotomy in Medical College Kolkata	08 Months

Secondary Outcome Measures

Name	Time	Method
Hemodynamic Parameter & Side effects of any	June 2025 TO January 2026

Trial Locations

Locations (1)

Medical College Kolkata; 🇮🇳 Kolkata, WEST BENGAL, India

Medical College Kolkata

🇮🇳Kolkata, WEST BENGAL, India

Dr Chayan Das

Principal investigator

08420222364

chayan.dcd@gmail.com