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Susceptibility of Ceftriaxone on infections

Not Applicable
Conditions
Health Condition 1: B950- Streptococcus, group A, as the cause of diseases classified elsewhere
Registration Number
CTRI/2022/04/041997
Lead Sponsor
Alkem Laboratories
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

180 Non-repetitive clinical samples such as blood, urine, respiratory samples, tissue, pus, cerebrospinal fluid (CSF), ascetic fluid etc.

Exclusion Criteria

Clinical isolates from repeat cultures performed during in-patient follow-up that were previously recruited into the study

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
1. To evaluate in vitro susceptibility of Ceftriaxone alone and Ceftriaxone in combination with Tazobactam and Sulbactam against gram positive and gram negative bacteria <br/ ><br>2. Antibiotic sensitivity of Ceftriaxone alone and Ceftriaxone in combination with Tazobactam and Sulbatam in extended-spectrum beta-lactamase (ESBL)- and metallo-beta-lactamse (MBL)-producing isolates.Timepoint: 1. Minimum inhibitory concentration of Ceftriaxone alone and Ceftriaxone in combination with Tazobactam and Sulbactam against gram positive and gram negative bacteria using E-Test Method <br/ ><br>2. Minimum inhibitory concentration of Ceftriaxone alone and Ceftriaxone in combination with Tazobactam and Sulbactam in gram negative bacteria extended-spectrum beta-lactamase (ESBL)- and metallo-beta-lactamse (MBL)-producing isolates.
Secondary Outcome Measures
NameTimeMethod
1. To evaluate in vitro susceptibility of Ceftriaxone alone and Ceftriaxone in combination with Tazobactam and Sulbactam compared to other broad spectrum antibiotics such as Amoxycillin clavulanate, Cefotaxime, Piperacillin Tazobactam, Cefipime against gram positive and gram negative bacteria.Timepoint: To evaluate minimum inhibitory concentration of Ceftriaxone alone and Ceftriaxone in combination with Tazobactam and Sulbactam against gram positive and gram negative bacteria using E-Test Method broad spectrum antibiotics such as Amoxycillin clavulanate, Cefotaxime, Piperacillin Tazobactam, Cefipime against gram positive and gram negative bacteria
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