Study comparing antibiotics versus placebo at time of catheter removal post robotic prostate removal

Not Applicable

• Conditions: urinary tract infection; prostate cancer; Infection - Studies of infection and infectious agents; Cancer - Prostate

• Registration Number: ACTRN12619000768190
• Lead Sponsor: A/Prof John Yaxley

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-05-23
• Last Update Posted: 15 July 2019

Recruitment & Eligibility

• Status: ot yet recruiting
• Sex: Male
• Target Recruitment: 800

Inclusion Criteria

Men undergoing robot assisted laparoscopic radical prostatectomy at the Wesley Hospital

Exclusion Criteria

non-robotic prostatectomy
positive preoperative urine culture
previous allergy to ceftriaxone

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
symptomatic urinary tract infection (UTI)<br>- positive urine culture and<br>- positive lower urinary tract symptoms (weekly international prostate symptom score) and/or systemic infective symptoms assessed by research fellow .<br><br>*this is a composite primary outcome[first 4 weeks post robot assisted laparoscopic radical prostatectomy <br>- urine sample will be collected at time of trial of void and weekly for four weeks post prostatectomy unless the participant becomes symptomatic then it will be repeated according to standard of care for UTI management <br>- participants will be assessed for symptoms as a single assessment at time of trial of void and they will be advised to self report any signs or symptoms of UTI to treating urologist or GP in the followup period]

Secondary Outcome Measures

Name	Time	Method
asymptomatic bacteriuria<br>- positive urine culture <br>- without any evidence of new lower urinary tract symptoms or systemic infective symptoms - participants will be asked at trial of void about these symptoms in a study specific questionnaire and will be advised to self report any signs or symptoms of UTI to treating urologist or GP in the followup period[30 days following robot assisted laparoscopic radical prostatectomy ]