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Clinical Trials/NCT05198661
NCT05198661
Recruiting
Not Applicable

Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis Collection

Hospices Civils de Lyon16 sites in 1 country3,500 target enrollmentAugust 2, 2022

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Paraneoplastic Neurological Syndromes or Autoimmune Encephalitis
Sponsor
Hospices Civils de Lyon
Enrollment
3500
Locations
16
Primary Endpoint
Blood Samples
Status
Recruiting
Last Updated
2 years ago

Overview

Brief Summary

Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.

Registry
clinicaltrials.gov
Start Date
August 2, 2022
End Date
August 2, 2032
Last Updated
2 years ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patient with consent
  • Patient with well-characterized antibodies in serum or cerebrospinal fluid or not
  • Patient with neurological disorder compatible with PNS or auto-immune encephalitis

Exclusion Criteria

  • Refusal of consent
  • Patient under guardianship

Outcomes

Primary Outcomes

Blood Samples

Time Frame: 10 years

Assessment of biocollection of blood samples

Cerebrospinal fluid biocollection

Time Frame: 10 years

Assessment of biocollection of Cerebrospinal fluid

Secondary Outcomes

  • Scientific collaboration(10 years)
  • Scientific(10 years)

Study Sites (16)

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