Paraneoplastic Neurological Syndromes and Autoimmune Encephalitis Collection
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Paraneoplastic Neurological Syndromes or Autoimmune Encephalitis
- Sponsor
- Hospices Civils de Lyon
- Enrollment
- 3500
- Locations
- 16
- Primary Endpoint
- Blood Samples
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Numerous neurological disorders affecting the central and peripheral nervous system can be attributed to the immune system through multiple effector mechanisms. However, current treatments could be drastically improved by faster and more accurate diagnosis. The sample collection will benefit to patients with rare neuroimmune syndromes such as Autoimmune Encephalitis (AE) and Paraneoplastic Neurological Syndromes (PNS) leading to a better and early diagnosis, as well as treatment improvement.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Patient with consent
- •Patient with well-characterized antibodies in serum or cerebrospinal fluid or not
- •Patient with neurological disorder compatible with PNS or auto-immune encephalitis
Exclusion Criteria
- •Refusal of consent
- •Patient under guardianship
Outcomes
Primary Outcomes
Blood Samples
Time Frame: 10 years
Assessment of biocollection of blood samples
Cerebrospinal fluid biocollection
Time Frame: 10 years
Assessment of biocollection of Cerebrospinal fluid
Secondary Outcomes
- Scientific collaboration(10 years)
- Scientific(10 years)