Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study

Not Applicable

Not yet recruiting

• Conditions: Wound Healing Complication; Oral Surgery; Third Molar Extraction; Oral Infection

• Registration Number: NCT06864559
• Lead Sponsor: Universidad de Granada

Brief Summary

Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used in Oral Surgery (Silk, non-absorbable polyamide monofilament and non-absorbable expanded polytetrafluoroethylene).

Detailed Description

The general or primary objective is:

• To compare 3 non-absorbable suture materials used in oral surgery: silk, polyamide monofilament and expanded polytetrafluoroethylene.

The specific or secondary objectives are:

* To evaluate how each type of suture influences wound healing and the patient's postoperative period.

* To study bacterial colonization in each type of suture.

* To determine the tissue reaction and clinical characteristics of each suture.

Study Timeline

• Study First Submitted: 2025-02-22
• Status Verified: 2025-03
• Study Start: 2025-03-01
• Study First Submitted QC: 2025-03-03
• Last Update Submitted: 2025-03-03
• Study First Posted: 2025-03-07
• Last Update Posted: 2025-03-07
• Primary Completion: 2025-09-01
• Study Completion: 2025-12-01

Recruitment & Eligibility

• Status: NOT_YET_RECRUITING
• Sex: All
• Target Recruitment: 24

Inclusion Criteria

• Patients with indication for extraction of a third lower molar retained in an unfavorable position that requires a bayonet incision in the surgical procedure.
• Age: patients aged 18 years or older.
• ASA I patients (Classification of the American Society of Anesthesiology, 1979): healthy patients who tolerate stress well, without systemic pathology, no anxiety and in whom a therapeutic modification is not necessary.

Exclusion Criteria

• Pregnant or breastfeeding women.
• Smoking patients.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
Bacterial colonization	7 days.	Microbiological analysis: CFU and qPCR bacterial count.
Level of inflammation	7 days.	The degree of soft tissue inflammation was assessed using Visual Analogue Scale (VAS).