The Influence of Meibomian Gland Expression on Corneal Aberrations in MGD Patients
- Conditions
- Meibomian Gland Dysfunction
- Registration Number
- NCT05028491
- Lead Sponsor
- Wenzhou Medical University
- Brief Summary
To evaluate the influence of corneal-aberrations before and after the meibomian gland thermal massage treatment.
- Detailed Description
62 MGD patients treated with meibomian gland thermal massage once a week for 3 to 4 weeks were recruited.The Ocular Surface Disease Index questionnaire; tear film assessment encompassing tear meniscus height and non-invasive keratograph breakup time ; meibography score,corneal fluorescein staining; the Schirmer I test ; expressible meibomian gland, and quality ,anterior and total corneal aberrations were evaluated before and after treatment.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 62
- tear break-up time (BUT) ≤10 seconds or Schirmer I test (SIT) ≤10 mm, the presence of dry eye symptoms, and fluorescein staining (FL) score <3 points and at least one lid margin abnormality and poor meibomian gland expressibility
- eyelid structure abnormal(Entropion , ectropion);
- having received any other treatment for MGD within three months
- history of ocular surgery
- contact lens use
- ocular infection
- any type of corneal scarring
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method corneal aberration corneal aberrations baseline and 1 week after treatment Corneal aberrations were measured with a Pentacam。 The anterior corneal wavefront aberration was expanded with normalized Zernike polynomials.The corneal aberration from 3rd to 6th order were recorded as the root mean square (RMS) for analysis.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Eye Hospital of Wenzhou Medical College
🇨🇳Wenzhou, Zhejiang, China