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MASSACHUSETTS EYE AND EAR INFIRMARY

🇺🇸United States

Country: 🇺🇸United States

Ownership: -

Established: 1824-01-01

Employees: -

Market Cap: -

Website: http://www.masseyeandear.org/

Clinical Trials

Assessing the Utility of Plasma ctHPVDNA for Anal Cancer Screening

Recruiting

Conditions: Anal Dysplasia

First Posted Date: 2025-05-14

Last Posted Date: 2025-05-14

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 101

Registration Number: NCT06971276

Locations: 🇺🇸
Department of Infectious Diseases, Mass General Hospital, Boston, Massachusetts, United States

Improving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mapping Strategy

Not Applicable

Recruiting

Conditions: Deafness
Cochlear Hearing Loss

First Posted Date: 2025-05-07

Last Posted Date: 2025-05-09

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 48

Registration Number: NCT06960616

Locations: 🇺🇸
Mass Eye and Ear, Boston, Massachusetts, United States

Subconjunctival Humira for Boston Keratoprosthesis

Phase 1

Not yet recruiting

Conditions: Penetrating Keratoplasty
Multiple Graft Failure
Ocular Cicatricial Pemphigoid
Stevens-Johnson Syndrome

Interventions: Drug: Adalimumab Injection

First Posted Date: 2025-04-13

Last Posted Date: 2025-04-13

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 8

Registration Number: NCT06926478

Locations: 🇺🇸
Massachusetts Eye and Ear, Boston, Massachusetts, United States

ctDNA in Cutaneous Squamous Cell Carcinoma

Recruiting

Conditions: Cutaneous Squamous Cell Carcinoma

First Posted Date: 2025-03-25

Last Posted Date: 2025-03-26

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 60

Registration Number: NCT06875609

Locations: 🇺🇸
Massachusetts Eye and Ear, Boston, Massachusetts, United States

The Glaucoma and Retinopathy Screening Study

Not Applicable

Recruiting

Conditions: Glaucoma

First Posted Date: 2025-03-18

Last Posted Date: 2025-07-02

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 2000

Registration Number: NCT06882356

Locations: 🇺🇸
Brigham and Women's Primary Care Associates of Longwood, Boston, Massachusetts, United States

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

Phase 2

Not yet recruiting

Conditions: Corneal Transplant Failure

First Posted Date: 2024-12-31

Last Posted Date: 2024-12-31

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 96

Registration Number: NCT06753916

Locations: 🇺🇸
University of California Irvine - Gavin Herbert Eye Institute, Irvine, California, United States
🇺🇸
The University of California Los Angeles - Doris Stein Eye Research Center, Los Angeles, California, United States
🇺🇸
University of Miami - Bascom Palmer Eye Institute, Miami, Florida, United States

and more 7 locations

Measurable Residual Disease Detection Using Tumor-Informed ctDNA Surveillance After Curative-Intent Treatment in HPV-Independent Squamous Cell Carcinoma of the Head and Neck

Recruiting

Conditions: Squamous Cell Carcinoma of Head and Neck

First Posted Date: 2024-12-20

Last Posted Date: 2025-05-18

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 75

Registration Number: NCT06744296

Locations: 🇺🇸
Massachusetts Eye and Ear, Boston, Massachusetts, United States

CtDNA Liquid Biopsy for Early Assessment of Residual Disease in HPV-associated Head and Neck Cancer (Clear-HPVca)

Completed

Conditions: HPV Positive Oropharyngeal Squamous Cell Carcinoma

First Posted Date: 2024-12-12

Last Posted Date: 2024-12-12

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 103

Registration Number: NCT06730412

Locations: 🇺🇸
Department of Otolaryngology - Head and Neck Surgery, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

Testing Effectiveness of a Stochastic Noise Stimulator to Immediately Improve Balance and Gait

Not Applicable

Not yet recruiting

Conditions: Vestibular Disorder
Aging

First Posted Date: 2024-11-14

Last Posted Date: 2025-07-02

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 120

Registration Number: NCT06688578

Locations: 🇺🇸
Johns Hopkins Medicine, Baltimore, Maryland, United States
🇺🇸
Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts, United States

The Safety and Efficacy of Intravitreal Topotecan for the Treatment of Proliferative Vitreoretinopathy

Phase 1

Not yet recruiting

Conditions: Rhegmatogenous Retinal Detachment
Proliferative Vitreoretinopathy
Proliferative Vitreo-Retinopathy

Interventions: Drug: Topotecan

First Posted Date: 2024-05-22

Last Posted Date: 2024-11-25

Lead Sponsor: Massachusetts Eye and Ear Infirmary

Target Recruit Count: 50

Registration Number: NCT06425419

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