NCT00617487
Unknown
Not Applicable
Stress Echocardiography in the Early Identification of Pulmonary Arterial Hypertension in Systemic Sclerosis
Fondazione IRCCS Policlinico San Matteo di Pavia2 sites in 1 country200 target enrollmentDecember 2007
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Systemic Sclerosis
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
- Enrollment
- 200
- Locations
- 2
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to evaluate the role of stress echocardiography, compared to standard echocardiography in the early identification of pulmonary arterial hypertension in systemic sclerosis. To evaluate the role of BNP in this setting.To analyze data recorded with respect to the parameters commonly used for SSc evaluation (eg thorax HRCT, pulmonary function tests + DLCO, nailfold capillaroscopy, etc); these parameters are available starting for 1999.
Investigators
Carlomaurizio Montecucco
Director, Dept. of Rheumatology
Fondazione IRCCS Policlinico San Matteo di Pavia
Eligibility Criteria
Inclusion Criteria
- •Patients with systemic sclerosis according to LeRoy criteria
Exclusion Criteria
- •Pregnancy
- •Significant valvular disease
- •Low left ventricular function upon echocardiography (ejection fraction\<55%)
- •History of atrial fibrillation, myocardial infarction, pulmonary thromboembolisms, neoplasia or severe hepatic disease.
Outcomes
Primary Outcomes
Not specified
Study Sites (2)
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