Laser Therapy for Patients With Systemic Lupus Erythematosus

Not Applicable

Completed

• Conditions: Systemic Lupus Erythematosus; Muscle Pain; Chewing Function
• Interventions: Device: GaAlAs semiconductor diode laser device

• Registration Number: NCT04453215
• Lead Sponsor: Dr. Merve Benli

Brief Summary

Systemic lupus erythematosus (SLE) is a chronic, autoimmune disease that has detrimental effects on connective tissue and other organs. The musculoskeletal system is one of the most affected systems in this group of patients including the temporomandibular joint. The most common symptoms when muscle involvement in SLE are muscle atrophy decreased muscle strength and myopathy. SLE activity and long-term corticosteroid use are thought to be responsible for these symptoms, thus, SLE patients are accepted to be at higher risk for temporomandibular joint disorders (TMD). Low-level laser therapy(LLLT) is frequently used in the treatment of TMD due to its pain relief and anti-inflammatory effect. Thus, in this study, LLLT has been used to evaluate this treatment modality on the chewing function and pain values of SLE patients with myogenic TMD.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-01-12
• Primary Completion: 2019-12-23
• Study Completion: 2020-03-15
• Study First Submitted: 2020-06-28
• Study First Submitted QC: 2020-06-28
• Study First Posted: 2020-07-01
• Status Verified: 2021-11
• Last Update Submitted: 2021-11-02
• Last Update Posted: 2021-11-10

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 91

Inclusion Criteria

• Having myogenic temporomandibular joint disorder,
• Following a stable medical regime,
• Showing minimum pain intensity of 50 mm on the visual analog scale.

Exclusion Criteria

• Having concurrent systemic diseases,
• Using antimalarial drugs,
• Wearing removable prosthesis,
• History of facial trauma.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
test group	GaAlAs semiconductor diode laser device	SLE patients treated with infrared laser irradiation
placebo group	GaAlAs semiconductor diode laser device	SLE patients treated with red laser irradiation

Primary Outcome Measures

Name	Time	Method
pain value	2 months	Pain intensity was evaluated by using Visual Analog Scale(VAS).
chewing function	2 months	The chewing function was evaluated by measuring the geometric mean diameter of crushed test food.

Trial Locations

Locations (1)

Istanbul university,Faculty of Dentistry; 🇹🇷 Fatih, Turkey