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Clinical Trials/NCT06129318
NCT06129318
Completed
Not Applicable

Investigation of the Effects of Pharmaceutical Care Provided by a Clinical Pharmacist on Stroke Patients

Marmara University1 site in 1 country260 target enrollmentMarch 10, 2021
ConditionsStroke

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Stroke
Sponsor
Marmara University
Enrollment
260
Locations
1
Primary Endpoint
Blood pressure
Status
Completed
Last Updated
2 years ago

Overview

Brief Summary

To evaluate the effects of the 1-year pharmaceutical care program offered by the clinical pharmacist to the patients admitted to the neurology service with the diagnosis of stroke, on medication adherence, quality of life, and clinical outcomes of the patients.

Detailed Description

The study was conducted as a parallel randomized controlled study in the Neurology Clinic of a University Hospital in Turkey. Patients were randomly assigned to intervention and usual care groups. While the patients in the usual care group are given routine health services by the neurologist during their hospitalization and for 1 year after discharge; In addition to these routine services, the intervention group was provided with pharmaceutical care by a clinical pharmacist during the same period. The study was always conducted by the same neurologist and clinical pharmacist. Patient medication adherence, quality of life, and clinical parameters were evaluated at the beginning of the study and at the 12th month.

Registry
clinicaltrials.gov
Start Date
March 10, 2021
End Date
April 30, 2023
Last Updated
2 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mesut Sancar

Prof. Dr.

Marmara University

Eligibility Criteria

Inclusion Criteria

  • being diagnosed with stroke,
  • being 18 years old or older,
  • being in the cognition to receive the training to be given

Exclusion Criteria

  • Not having adequate cognitive function such as dementia,
  • being pregnant, lactating,
  • having cancer.

Outcomes

Primary Outcomes

Blood pressure

Time Frame: 1, 3, 6, 9 and 12 months

Blood pressure was checked and recorded by a qualified nurse during the hospital stay and at control visits. Measurements were recorded as mmHg.

Medication Adherence

Time Frame: 3, 6, 9 and 12 months

Adherence to Stroke Prevention Medications (Anti platelets, Anticoagulants, Statins, antihypertensives, antidiabetics) measured by Morisky-Green-Levine Adherence Scale (1-4) where higher scores indicate higher levels of reported adherence.

HbA1c

Time Frame: 1, 3, 6, 9 and 12 months

HbA1c (glycated hemoglobin) value was collected from medical records and recorded as a percentage.

LDL cholesterol

Time Frame: 1, 3, 6, 9 and 12 months

Low density lipoprotein-cholesterol level was collected from medical records and recorded as mg/dL

Triglyceride

Time Frame: 1, 3, 6, 9 and 12 months

Triglyceride level was collected from medical records and recorded as mg/dL.

Body mass index

Time Frame: 1, 3, 6, 9 and 12 months

Body mass index (BMI) was collected from medical records and recorded as kg/m2

Secondary Outcomes

  • Drug Related Problem(1 year)
  • The National Institutes of Health Stroke Scale(24 hours before discharge, 3, 6, 9 and 12 months)
  • Measuring Quality of Life(3, 6 and 12 months)
  • Stroke Recurrence(1 year)

Study Sites (1)

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