PRF for Accelerating Palatal Healing
- Conditions
- Gingival Recession
- Registration Number
- NCT02712242
- Lead Sponsor
- Cukurova University
- Brief Summary
Backgroung: Various agents are used to reduce post-operative complications associated with palatal donor site surgery for free gingival graft (FGG) harvesting. This study was conducted to evaluate the effects of platelet-rich fibrin (PRF) on palatal wound healing.
- Detailed Description
125 patients with isolated recessions were treated. The connective tissue graft was obtained by the de-epithelialization of a free gingival graft in both groups. Three different hemostatic treatments were randomized; PRF with cyanoacrilate adhesive (PRF group, n:42), cyanoacrilate adhesive alone (BC group, n:42) and sterile wet gauze compression (WG group, n:41). Immediate and delayed bleeding, pain, epithelialization, feeding habits and sensation scores were recorded for different time points.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 125
- no contraindications for periodontal surgery;
- full-mouth plaque score of <10%
- full-mouth bleeding score of <15%.
- previously undergone surgery for a graft harvested from the palate
- presence of systemic disease or taking medication known to interfere with periodontal health
- smokers
- possible coagulation disorders
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Epithelialization One month Assessed according to the toluedine blue coloring
- Secondary Outcome Measures
Name Time Method Delayed bleeding 1 week Bleeding assesment for post-operative one week
Sensibility disorders One month visual analogue scale scores
Pain 3 months Visual Analague Scale scores
Immediate Bleeding 1 hour Bleeding assesment for post-operative one hour
feeding habits One month visual analogue scale scores