Antibacterial effects of elastomeric ligatures coated with bacterial nanocellulose

Phase 3

Recruiting

• Conditions: Antibacterial effects of elastomeric ligatures coated with Kombucha-synthesized bacterial nanocellulose against streptococcus mutans.

• Registration Number: IRCT20181121041713N5
• Lead Sponsor: Shiraz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 13 November 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 72

Inclusion Criteria

Male and female patients
Age 15 to 30 years
non pregnant
No significant medical history or drug use
No anti-inflammatory or antibiotic medications taken within ? months prior to the study
No chewing gum or mouthwash use in the week before and during the study
habit of brushing twice daily with fluoride toothpaste
No history of periodontal therapy or current periodontal disease Probing depth less than ? mm across the entire dentition
No gingivitis or active carious lesion
Gingival index and plaque index (Silness-Löe) value <1

Exclusion Criteria

Diseases and medication use likely to affect dental biofilm
Pregnancy
Poor oral hygiene
Active periodontal disease
Severe crowding of anterior teeth or malposition of the lateral incisor likely to interfere with the cleaning of the tooth surface
Smoking
History of mouth breathing

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Bacterial colony counting. Timepoint: The beginning of the study and days 7, 14, 21 and 28. Method of measurement: Counting the number of bacterial colonies after sampling.