Antibacterial activity of Novel herbal intracanal medicaments against endodontic pathogens.
Phase 1
- Conditions
- Health Condition 1: Z759- Unspecified problem related to medical facilities and other health care
- Registration Number
- CTRI/2021/12/038772
- Lead Sponsor
- DrSheetal Ghivari
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients aged between 20 to 59 years (mean 27 years)
2.Patients without any systemic abnormality
3.Patients with weeping canals, and with periapical lesions
4.No history of antibiotics for past 1months
5.Single rooted teeth were selected
6.Negative response to thermal tests
7.Sufficient tooth coronal tooth structure to apply rubber dam
8. No history of endodontic treatment
9. Tooth with complete root formation
Exclusion Criteria
1.Patients above 60 years
1.2.Patients with systemic medications including antibiotics
3.Patients with history of systemic ailments such as Hypertension, Diabetes mellitus, Asthma etc
4.Patients with history of cardiac surgeries(Bypass, Valve replacements, Stent)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Reduction in pain including percussion tenderness <br/ ><br>reduction in the infection <br/ ><br>without any pus discharge <br/ ><br>Reduction in the size of periapical lesion. <br/ ><br>Timepoint: with in 8 days <br/ ><br>
- Secondary Outcome Measures
Name Time Method <br/ ><br>Complete periapical healing <br/ ><br>Formation of new bone and regeneration of periodontal fibers.Timepoint: with in 6 months to 1 year depending on the size of periapical lesion.