Effect of Colloid Versus Crystalloid on Coagulation in Elective Urological Surgery
Phase 4
Completed
- Conditions
- Disorders of Coagulation
- Interventions
- Drug: Lactated RingerDrug: Hydroxyethylstarch
- Registration Number
- NCT02009033
- Lead Sponsor
- K. C. Rasmussen
- Brief Summary
The purpose of this study is to investigate the effect of thin fluid with starch versus thin fluid without starch on coagulation in elective surgery when the patient is normovolæmic during operation.
- Detailed Description
The primary goal is to register coagulation on basis of blood samples inclusive thromboelastography results.
The secondary goal is to register blood loss and use of blood products during operation.
The trial concerns 40 patients.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
- Patient older than 18 years.
- Indication for elective surgery with removal of the urine bladder.
- Patient without anticoagulative, acethylsalisylsyre or NSAID medicine during the last 5 days,if using.
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Exclusion Criteria
- Cerebral haemorrhage
- Renal insufficiency demanding dialysis
- Manifest cardiac and hepatic insufficiency
- Disturbance in coagulation
- Hypernatriæmi
- Hyperchloræmi
- Pregnant or nursing
- Allergic to hydroxyethylstarch
- Participating in another trial-if interferring the present trial
- Incapable of managing his own affairs.
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Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Ringer's lactate Lactated Ringer Fluid therapy during operation Ringer's lactate Hydroxyethylstarch Fluid therapy during operation
- Primary Outcome Measures
Name Time Method Estimate coagulation on basis of bloodsamples 6 months
- Secondary Outcome Measures
Name Time Method Estimate coagulation by bloodloss and need for transfusion 6 months