The effect of Levothyroxine on reduction of Thyroid nodule's volume

Not Applicable

• Conditions: Thyroid nodule.; Disorders of thyroid gland; E00-E07

• Registration Number: IRCT2015100918858N2
• Lead Sponsor: Yazd Shahid Sadoughi Univercity of Medical Science

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 132

Inclusion Criteria

1.be euthyroid; 2.non malignant nodule; 3.the age range of 18 to 65 years old.
Exclusion criteria:1.treatment with levothyroxin or methimazole; 2.patients of iodine deficiency areas; 3.history of surgery on thyroid; 4.history of head and neck radiation; 5.pregnancy; 6.nodule's cystic portion>20%; 7.heart disease(IHD-arrhythmia); 8.osteoporosis; 9. more than 3 nodules in every thyroid's lobe.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Size of thyroid nodules. Timepoint: At the beginnig of the study and after 6 &12 months. Method of measurement: Ultrasonography.;Volume of thyroid nodule. Timepoint: At the beginnig of the study and after 6 &12 months. Method of measurement: Ultrasonography.

Secondary Outcome Measures

Name	Time	Method
TSH. Timepoint: At the beginnig of the study; 3 months interval in treatment group and 6 months interval in control group. Method of measurement: Laboratory kit.;Anti TPO. Timepoint: At the beginnig and the end of the study. Method of measurement: Laboratory kit.;T4. Timepoint: At the beginnig of the study; 3 months interval in treatment group and 6 months interval in control group. Method of measurement: Laboratory kit.;T3. Timepoint: At the beginnig of the study; 3 months interval in treatment group and 6 months interval in control group. Method of measurement: Laboratory kit.