ISRCTN08877757已完成不适用

Impact of EECP-treatment (Enhanced External Counterpulsation) on myocardial adaptive arteriogenesis in patients suffering from stable symptomatic coronary heart disease

Charite - University Medicine Berlin (Charite - Universitatsmedizin Berlin) (Germany)0 个研究点目标入组 21 人开始时间: 2007年12月18日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•1. Patients of both genders
•2. Age greater than 30 to less than 80 years
•3. Suffering from stable coronary vessel disease for more than 3 months
•4. With an angiographically diagnosed haemodynamic significant stenosis of at least one epicardial vessel
•5. An objective positive test for stress-induced ischaemic imaging and pathological Fractional Flow Reserve (FFR less than 0.8)

•1. Unstable angina
•2. After aorto-coronary bypass grafting
•3. No previous Q-wave infarction in the area assessed for coronary collaterals
•4. Non-ischaemic left ventricle dysfunction Ejection Fraction (EF) less than 35%, fluid overload
•5. Tricuspid and aortic valve insufficiency greater than grade II and aortic valve stenosis greater than grade II
•6. Relevant stenosis of the aorta abdominalis or aorta thoracica, coarctatio aortae
•7. Symptomatic angiopathy of the lower limb (neuropathy, vasculitis, symptomatic Peripheral Arterial Disease [PAD] ankle pressure less than 80 mmHg)
•8. Chronic venous insufficiency grade greater than III, symptomatic varicosis, thrombosis, occlusion of vena cava inferior, phlebitis
•9. Evident lesions at the lower extremity (ulcera, big scar, etc.)
•10. Diabetic retinopathy
•11. Anticoagulation International Normalised Ratio (INR) greater than 3 or less and bleeding symptoms, disturbed homeostasis
•12. Orthopaedic disease (hip, knee)
•13. Severe systemic disease
•14. Severe hypertension greater than 180 mmHg
•15. Status post cerebral bleeding
•16. Pregnancy
•17. Mental retardation or dementia
•18. Severe kinking of coronary vessels
•19. Atrial fibrillation
•20. Pacemaker (PM)/Implantable Cardioverter Defibrillator (ICD), metal valve
•21. Acute renal insufficiency, progressive renal insufficiency, chronic renal insufficiency - cut off creatinine 2 mg/dl

发起方

Charite - University Medicine Berlin (Charite - Universitatsmedizin Berlin) (Germany)