Impact of a Low Carbohydrate Breakfast on Glucose Control in Type 2 Diabetes

Not Applicable

Completed

• Conditions: Type2 Diabetes
• Interventions: Behavioral: Low Carbohydrate Breakfast; Behavioral: Guidelines Breakfast

• Registration Number: NCT02982330
• Lead Sponsor: University of British Columbia

Brief Summary

Large glucose excursions at breakfast are prevalent in type 2 diabetes and can contribute to sustained hyperglycaemia across the day. Lowering consumption of dietary carbohydrate is known to reduce post-meal glucose excursions but it is unknown whether lowering the carbohydrate at breakfast only will impact subsequent post meal glucose excursions throughout the day. The aim of this study is to examine, under free living conditions and using typical dietary patterns, whether eating a breakfast low in carbohydrate can lower daily post-meal glycemia when compared to consuming a low-fat breakfast (per the current diabetes guidelines).

Detailed Description

Not available

Study Timeline

• Study Start: 2016-11
• Study First Submitted: 2016-11-29
• Study First Submitted QC: 2016-11-30
• Study First Posted: 2016-12-05
• Primary Completion: 2017-07
• Study Completion: 2017-08
• Status Verified: 2017-10
• Last Update Submitted: 2017-10-12
• Last Update Posted: 2017-10-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 27

Inclusion Criteria

• Physician-diagnosed Type 2 Diabetes (>6 months)

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Exclusion Criteria

• Exogenous Insulin
• A1c > 9%
• Cardiovascular, liver, or renal other disease
• Breakfast and meal skippers

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
Low Carbohydrate Breakfast	Guidelines Breakfast	Breakfast composition containing \<10% carbohydrate, 75% fat, 15% protein Matched calories
Low Carbohydrate Breakfast	Low Carbohydrate Breakfast	Breakfast composition containing \<10% carbohydrate, 75% fat, 15% protein Matched calories
Guidelines Breakfast	Low Carbohydrate Breakfast	Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories
Guidelines Breakfast	Guidelines Breakfast	Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories

Primary Outcome Measures

Name	Time	Method
Incremental area under the glucose curve (continuous glucose monitor)	24 hour (one day)

Secondary Outcome Measures

Name	Time	Method
Mean Blod Glucose (continuous glucose monitor)	24 hours (one day)

Trial Locations

Locations (1)

University of British Columbia, Okanagan.; 🇨🇦 Kelowna, British Columbia, Canada