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临床试验/NCT02982330
NCT02982330已完成不适用

Impact of a Low Carbohydrate Breakfast on Glucose Control in Type 2 Diabetes

University of British Columbia2 个研究点 分布在 1 个国家目标入组 27 人开始时间: 2016年11月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
27
试验地点
2
主要终点
Incremental area under the glucose curve (continuous glucose monitor)

研究概览

简要总结

Large glucose excursions at breakfast are prevalent in type 2 diabetes and can contribute to sustained hyperglycaemia across the day. Lowering consumption of dietary carbohydrate is known to reduce post-meal glucose excursions but it is unknown whether lowering the carbohydrate at breakfast only will impact subsequent post meal glucose excursions throughout the day. The aim of this study is to examine, under free living conditions and using typical dietary patterns, whether eating a breakfast low in carbohydrate can lower daily post-meal glycemia when compared to consuming a low-fat breakfast (per the current diabetes guidelines).

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Treatment
盲法
None

入排标准

年龄范围
30 Years 至 90 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Physician-diagnosed Type 2 Diabetes (>6 months)

排除标准

  • Exogenous Insulin
  • A1c > 9%
  • Cardiovascular, liver, or renal other disease
  • Breakfast and meal skippers

研究组 & 干预措施

Low Carbohydrate Breakfast

Experimental

Breakfast composition containing <10% carbohydrate, 75% fat, 15% protein Matched calories

干预措施: Low Carbohydrate Breakfast (Behavioral)

Low Carbohydrate Breakfast

Experimental

Breakfast composition containing <10% carbohydrate, 75% fat, 15% protein Matched calories

干预措施: Guidelines Breakfast (Behavioral)

Guidelines Breakfast

Active Comparator

Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories

干预措施: Low Carbohydrate Breakfast (Behavioral)

Guidelines Breakfast

Active Comparator

Breakfast composition containing 55% carbohydrate, 30% fat, 15% protein Matched calories

干预措施: Guidelines Breakfast (Behavioral)

结局指标

主要结局

Incremental area under the glucose curve (continuous glucose monitor)

时间窗: 24 hour (one day)

次要结局

  • Mean Blod Glucose (continuous glucose monitor)(24 hours (one day))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jonathan Little

Dr Jonathan P Little

University of British Columbia

研究点 (2)

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