Prize Reinforcement Contingency Management for Cocaine Dependence: a 24-week Randomized Controlled Trial

Not Applicable

Completed

• Conditions: Cocaine-related Disorders
• Interventions: Behavioral: Cognitive behavioral therapy (CBT)

• Registration Number: NCT00877435
• Lead Sponsor: University Hospital, Basel, Switzerland

Brief Summary

The purpose of this study is to determine whether prize-based contingency management (prizeCM) combined with cognitive behavioral therapy (CBT) is more effective in the treatment of of cocaine-dependent patients compared to CBT only. Patients were randomized to prizeCM + CBT (experimental group) or to CBT (control group) an treated over 24 weeks. It is the first trial of this type in Europe.

Detailed Description

Not available

Study Timeline

• Study Start: 2008-09
• Study First Submitted: 2009-04-06
• Study First Submitted QC: 2009-04-06
• Study First Posted: 2009-04-07
• Primary Completion: 2013-08
• Study Completion: 2014-10
• Status Verified: 2015-01
• Last Update Submitted: 2015-01-28
• Last Update Posted: 2015-01-29

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• cocaine dependence, aged 18 or older, other dependences

Exclusion Criteria

• severe somatic, brain, or psychiatric disease, attention deficit disorders with medication methylphenidate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
2	Cognitive behavioral therapy (CBT)	Cognitive behavioral therapy (CBT)
1	Cognitive behavioral therapy (CBT)	Cognitive behavioral therapy (CBT) + prize-based contingency management (prizeCM)

Primary Outcome Measures

Name	Time	Method
retention in treatment, cocaine abstinence	24 weeks	cocaine abstinence: at least 3 consecutive weeks of cocaine abstinence, the maximum number of weeks of continous abstinence and proportions of cocaine-free urine samples during the entire 24-week and at 6-month follow-up.

Secondary Outcome Measures

Name	Time	Method
patients' satisfaction with the therapy, clinical measures	24 weeks	patients' satisfaction with prize-based contingency management and with CBT

Trial Locations

Locations (2)

Fondation Phenix; 🇨🇭 Geneva, Switzerland

Universitäre Psychiatrischen Kliniken; 🇨🇭 Basel, Switzerland