TCTR20170227005已完成未知
Impact of POR*28 and CYP3A5 polymorphisms on trough concentration to dose ratio of tacrolimus in Thai kidney transplant recipients
Assoc. Prof. Dr. Atiporn Ingsathit0 个研究点目标入组 200 人开始时间: 2017年2月27日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 200
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 0 N/A (No limit)（—）
- 性别
- All
入选标准
- •Eligible patients are those who received tacrolimus for at least 3 months after their kidney transplantation together with mycophenolate mofetil or mycophenolate sodium.
排除标准
- •1) Multi-organ transplantation
- •2) Hyper-acute graft rejection
- •3) History of cirrhosis, hepatocelluar carcinoma or hepatitis
- •4) Severely impaired liver function
- •5) Hypoalbuminemia (serum albumin <3g/dl)
- •6) Receiving co-medications that interfere the pharmacokinetic of tacrolimus except for methylprednisolone, prednisolone, and omeprazole
研究者
相似试验
已完成
不适用
Genetic study in renal transplant patientsCTRI/2018/04/013495Seth GS Medical College and KEM Hospital150
招募中
2 期
Effects of genetic polymorphism of CYP3A5 and UGT1A9 in brain-death donor and liver transplant recipients on pharmacokinetic profiles of tacrolimus and mycophenolate at steady state post-transplantatioThai liver transplant patients (cadaveric liver transplant)Thai liver transplant patients (cadaveric liver transplant),CYP3A5 and UGT1A9 polymorphisms,PharmacokineticsTCTR20190707002Rachadapisek Sompote Fund.20
进行中（未招募）
1 期
The influence of CYP3A5 and ABCB1 genotype on the pharmacokinetics of twice daily Tacrolimus and Advagraf - Pharmacogenetics of twice daily Tacrolimus and AdvagrafRenal transplantation.MedDRA version: 14.1 Level: LLT Classification code 10023438 Term: Kidney transplant System Organ Class: 100000004865EUCTR2009-013461-25-GBSt. George's, University of London330
Enrolling By Invitation
不适用
Impact of CYP3A5 polymorphisms on intra-patient variability of tacrolimus pharmacokinetics in kidney transplant recipientsage over 18 years old,received immunosuppressive therapy based on twice-daily tacrolimus (Prograf®)tacrolimuspharmacokineticsintrapatient variabilityCYP3A5TCTR20180619003Chulalongkorn University200
已完成
不适用
Healthy Volunteer CYP3A5 Genotype studyCTRI/2018/10/016104ithya Gogtay400