A randomised controlled trial to compare the cost-effectiveness of tricyclic antidepressants, selective serotonin re-uptake inhibitors and lofepramine

Not Applicable

Completed

• Conditions: Mental and behavioural disorders: Depression, anxiety, neuroses; Mental and Behavioural Disorders; Depression

• Registration Number: ISRCTN14453847
• Lead Sponsor: Department of Health (UK)

Brief Summary

2005 Results article in http://www.ncbi.nlm.nih.gov/pubmed/15876362 HTA monograph

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2003-04-25
• Study Completion: 2003-07-31
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 327

Inclusion Criteria

The sample group is of 327 patients who are prescribed antidepressant drugs by their general practitioner. The sociodemographic characteristics and other features of this group will be analysed, to evaluate whether the sample is representative of the wider population of general practice patients received antidepressant treatment.

Exclusion Criteria

Not provided at time of registration.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Quality of life and economic measures.<br> Clinical outcomes are being assessed through use of the Clinical Interview Schedule, Rviesed version; the Hospital Anxiety and Depression Scale; the Euroqol; and the SF-36 Quality of Life Scale. Use of health services is being assessed through patient-completed questionnaires, and through detailed examination of general practice medical records.<br>

Secondary Outcome Measures

Name	Time	Method
ot provided at time of registration.