Clinical effect of Acupuncture Pretreatment on sleep deprivation and the mechanism of immune protein regulation

Changchun University of Traditional Chinese Medicine0 个研究点开始时间: 待定最近更新: 2023年2月20日

适应症

试验速览

暂无简介。

•1. Healthy young male volunteers aged 18-30 years;
•2. The body mass index of subjects with body weight over 45kg was 18.5-23.9;
•3. The subjects should not have any congenital defects or chronic diseases within 3 years before enrollment, and should not have any pathological or abnormal clinical findings in physical examination, such as severe primary diseases of cardiovascular system, lung, liver, kidney and hematopoietic system;
•4. Subjects with no sleep disorder and Pittsburgh sleep quality index (PSQI) score < 5;
•5. Subjects with SDS score <= 50 and SAS score <= 53;
•6. Seven days before the start of the first clinical trial, participants must maintain normal night sleep time (between 21:00 and 09:00);
•7. Seven days before the start of the first clinical trial, participants must sleep at least seven hours every night;
•8. Non smoking subjects;
•9. The subjects who voluntarily sign the written informed consent;
•Note: those meeting the above 9 items at the same time will be included.

•1. Subjects who regularly drank alcohol (> 210g / week) within 6 months before enrollment. Beer (5% v / V): 250ml = 10g, Shaojiu (20% v / V): 50ml = 8g, wine (12% v / V): 125ml = 12g);
•2. Subjects who participated in another clinical study within 2 months before enrollment;
•3. Subjects who had donated whole blood within 2 months before enrollment, or had donated blood components within 1 month before enrollment;
•4. Subjects with sitting systolic blood pressure >= 140mmHg or diastolic blood pressure >= 90mmHg at the time of screening;
•5. Subjects who took prescription or non prescription drugs within 7 days before the first clinical trial;
•6. Subjects who had drinking history of caffeine, tea and wine within 7 days before the first clinical trial;
•7. Subjects who had received acupuncture treatment for any disease within 7 days before enrollment;
•8. Subjects with severe skin infection, weak constitution and a history of acupuncture sickness at acupoints;
•Note: any one of the above items is excluded.

发起方

Changchun University of Traditional Chinese Medicine