Retrospective Study of Acute Chest Pain in Extremely Critical Condition for More Than Ten Years

• Conditions: Aortic Dissection; Pulmonary Embolism; Acute Myocardial Infarction

• Registration Number: NCT02837120
• Lead Sponsor: Qilu Hospital of Shandong University

Brief Summary

Acute non-traumatic chest pain is a common kind of symptom in extremely critical condition, with various pathogenesis and different level of risk . Chest pain in high risk takes 1/3 of that. It mainly includes acute coronary syndrome (including myocardial infarction and unstable angina pectoris, accounted for over 95% of chest pain in high risk), aortic dissection, pulmonary embolism etc, and is in high lethality and deformity.

The investigators do the research :

1. To study the diagnosis and management condition of acute chest pain in extremely critical condition for last ten or more years in Qilu Hospital,Shandong University.

2. To discuss the significance of key accompanying symptoms(for example radiating pain, chest distress, sweating, nausea etc), physical signs and lab examination in early diagnosis and risk stratification of acute chest pain in extremely critical condition.

3. To study the effect factors of thrombus burden in STEMI patients, at the same time, creat a a simple, practical and scientific method of blood clots classification.

Detailed Description

Not available

Study Timeline

• Study Start: 2016-06
• Status Verified: 2016-07
• Primary Completion: 2016-07
• Study Completion: 2016-07
• Study First Submitted: 2016-07-07
• Study First Submitted QC: 2016-07-18
• Study First Posted: 2016-07-19
• Last Update Submitted: 2016-07-22
• Last Update Posted: 2016-07-25

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 7000

Inclusion Criteria

• Inpatients of Qilu Hospital, whose electronic medical records were searched out by terms of acute myocardial infarction, aortic dissection, pulmonary embolism and unstable angina in International Classification of Diseases(ICD)-10 code from Jan.2003 to Sep.2015.

Exclusion Criteria

• Patients whose medical records are false, omitted or uncompleted because of transference, death et al.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Diagnosis and management of acute chest pain diseases in extremely critical condition	A week after data collected	In-hospital mortality, hospitalization days

Secondary Outcome Measures

Name	Time	Method
Clinical characteristics of participants for demographics, medical history, examination results and investigations retrieved from electronic medical records	A week after data collected	Frequency of chest pain, sweating, nausea, radiating pain, dyspnea and temperature, pulse, respiration rates, blood pressure, value of blood glucose, D-Dimer, et al, on admission.
The predicted factors of thrombus burden in STEMI patients, and the influence of thrombus burden on mortality	A week after data collected	The relationship between value of leukocyte,glucose,lipid,blood pressure et al, all-cause mortality and thrombus burden.

Trial Locations

Locations (1)

Qilu Hospital of Shandong University; 🇨🇳 Jinan, Shandong, China