Therapeutic effect of Topiramate in refractory Obsessive Compulsive Disorder
Not Applicable
- Conditions
- Obcessive Compulsive Disorder.Obsessive Compulsive Disorder
- Registration Number
- IRCT2013012312252N1
- Lead Sponsor
- Isfahan University Of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
Obsessive Compulsive criteria according to DSM-IV-TR;
Be used maximum tolerated dose of SSRI or Clomipramine for at least 12 weeks;
moderate to severe symptoms according to Yale Brown Scale score more than 16;
informed consent
Exclusion criteria:primary diagnosis of psychotic or mood disorder(bipolar or MDD); subtance abuse or dependence; uncontrolled medical illness(e.g. DM,HTN,...); previous use of Topiramate; pregnancy or breastfeeding or who wants to be pregnant; convulsive disorder; suicidal thought; past history of renal stone
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Obsessive Compulsive Disorder severity. Timepoint: before intervention and after first,second and third month. Method of measurement: Yale Brown Scale and CGI scale.
- Secondary Outcome Measures
Name Time Method