Comparison of drugs, Fluvoxamine ans Sertraline in patients with OCD in terms of efficacy and effect on neuro-psychological functions.
Not Applicable
- Conditions
- Health Condition 1: F42- Obsessive-compulsive disorder
- Registration Number
- CTRI/2020/01/022890
- Lead Sponsor
- Government Medical College and Hospital Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Diagnosis of OCD as per Diagnostic and Statistical Manual of Mental Disorders-5
2. Treatment-naïve patients
3. Those consenting to participate
4. Age group of 18-55 years
5. Any gender
Exclusion Criteria
1. Depression, anxiety or any other psychiatric illness of diagnosable severity
2. Co-morbid intellectual disability
3. Co-morbid neurological disorder, organic brain syndrome, dementia, or epilepsy
4. Co-morbid substance dependence except caffeine and nicotine
5. Subjects with high, active suicidal risk
6. Subjects with severe medical, surgical or any other condition in which these medications are contraindicated
7. Pregnant and lactating females
8. Subjects who received ECT anytime during preceding three months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. To study severity of illness, neuropsychological functions and quality of life in patients with obsessive compulsive disorder. <br/ ><br>2. To study the effect of fluvoxamine and sertraline on severity of illness, neuropsychological functions and quality of life in patients with obsessive compulsive disorder. <br/ ><br> <br/ ><br> <br/ ><br>Timepoint: Baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 12 weeks <br/ ><br> <br/ ><br>
- Secondary Outcome Measures
Name Time Method 1. To study the association of socio demographic and clinical variables with severity of illness, neuropsychological functions and quality of life in patients with obsessive compulsive disorder. <br/ ><br>2. To compare effects of fluvoxamine and sertraline on above cited parameters. <br/ ><br>Timepoint: Baseline, 2 weeks, 4 weeks, 6 weeks, 8 weeks, 12 weeks