Postoperative pain after cesarean section :efficacy of S-ketamine at antihyperalgesic doses. - ND

• Conditions: Postoperative pain after cesarean section; MedDRA version: 6.1Level: PTClassification code 10006924

• Registration Number: EUCTR2006-005635-25-IT
• Lead Sponsor: POLICLINICO UNIVERSITARIO AGOSTINO GEMELLI

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2007-06-04
• Last Update Posted: 19 March 2012

Recruitment & Eligibility

• Status: ot Recruiting
• Sex: Female
• Target Recruitment: Not specified

Inclusion Criteria

parturients undergoing elective caesarean section ,aged 18-40, ASA I-II.
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range

Exclusion Criteria

-patients ASA III-IV (significant co-existing maternal cardiovascular, respiratory ,neurologic, endocrine, metabolic and psychiatric disease )

-pathologic pregnancy

-week gestation < 37

-absolute and relative contraindications to spinal anaesthesia

-patient refusal

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Main Objective: Difference in morphine consumption between groups.<br><br>Difference in pain threshold between groups at prefixed times.;Secondary Objective: Comparison between groups about:<br><br>lenght of spinal analgesia(time to first request of morphine).<br><br>maternal side effects;Primary end point(s): Efficacy of S-ketamine in lowering postoperative analgesic consumption and prevent hyperalgesia.