Study of Visceral Fat in type2diabetic Patients and Its Relation to Microvascular Complications

• Conditions: Visceral Fat; Insulin Resistance

• Registration Number: NCT06112197
• Lead Sponsor: Sohag University

Brief Summary

Study the correlation between METS IR and visceral fat in type 2 diabetes and its relation to microvascular complication

Detailed Description

The Metabolic Score for Insulin Resistance (METS-IR) is a metabolic index developed with the aim to quantify peripheral insulin sensitivity in humans; it was first described under the name METS-IR by Bello-Chavolla et al in 2018. It was developed by the Metabolic Research Disease Unit at the Institute National de Ciencias Médicas Salvador Zubirán and validated against the euglycemic hyperinsulinemic clamp and the frequently-sampled intravenous glucose tolerance test in Mexican population.It is a non-insulin-based alternative to insulin-based methods to quantify peripheral insulin sensitivity and an alternative to the Homeostatic Model Assessment (HOMA-IR) and the quantitative insulin sensitivity check index (QUICKI).

Very limited research correlate between visceral obesity and microvascular complications in type 2 diabetic patients and how can the metabolic score for insulin resistance predict visceral obesity and microvascular complications in type2 diabetic patients. In this study the investigators will search for these correlations.

Study Timeline

• Status Verified: 2023-10
• Study First Submitted: 2023-10-26
• Study First Submitted QC: 2023-10-26
• Last Update Submitted: 2023-10-31
• Study First Posted: 2023-11-01
• Last Update Posted: 2023-11-02
• Study Start: 2024-01-05
• Primary Completion: 2025-01-05
• Study Completion: 2025-06-05

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Age > 18 years Both male and female subjects Subjects capable of giving consent and voluntarily willing to participate in the study

Exclusion Criteria

• Chronic kidney disease patients Any nondiabetic nephropathy patients Patients affected by hypertension Patients affected by ocular disorders Neuropathies of other etiologies like chronic liver disease patients, alcoholics, or drug addicts Critically ill patients of type 2 diabetes mellitus Patients who have not given consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
correlation between METS IR and visceral fat in type 2 diabetes	one year	Study the cor relation between METS IR and visceral fat in type 2 diabetes and its relation to microvascular complication

Trial Locations

Locations (1)

Mahmoud Soliman; 🇪🇬 Sohag, Egypt