Serotonergic modulation of population receptive fields
- Conditions
- There is no specific disease being investigated
- Registration Number
- NL-OMON54157
- Lead Sponsor
- Spinoza Centre for Neuroimaging
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 40
Healthy english-speaking volunteers between 21 and 55 years old;
Male or female;
At least one previous experience with a hallucinogenic substance, but not in
the 4 weeks prior to the beginning of the study.
Personal, or first-degree relative with, diagnose of psychiatric conditions
(schizophrenia, bipolar disorders).
History of neurological disorders (including stroke, convulsion, epilepsy) as
well as concussion with loss of consciousness.
Used psychotropic drugs or medications over a period of 1 week prior to each
test session.
Currently using substances interacting with the metabolism of psilocybin or the
serotonergic system (e.g. monoamine oxidase inhibitors, SSRIs).
Contraindications for 7T MRI (e.g. claustrophobia, osteosynthetic material,
pacemaker, artificial cardiac valves, pregnancy, tinnitus).
Significant previous adverse response to a psychotropic substance.
Significant previous adverse response to fMRI scanning.
Participant does not speak English.
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method