Comparing the effects of pomegranate and orange juice in non-alcoholic fatty liver disease patients

Not Applicable

Conditions: non-alcoholic fatty liver disease.

Registration Number: IRCT201102232709N17

Lead Sponsor: Vice-chancellor for Research, Tehran University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 70

Inclusion Criteria

Inclusion Criteria: signing written informed consent, age between 30 and 65, diagnosis of non-alcoholic fatty liver disease by fatty infiltration on ultrasound and abnormal serum liver function tests (AST or ALT>30 u/l in men and >20 in women), no smoking, BMI= 25, no pregnancy or lactation, no use of dietary supplements one month prior to enrollment, not having diabetes, renal impairment, acute heart disease, thyroid disease, other form of liver disease (viral or autoimmune hepatitis, metabolic and hereditary liver disease) and any diseases that can affect on body weight, not having severe gaining or losing weight diet in the 3 month prior to the enrollment, no use of medication that could affect body weight in the 3 month prior to the enrollment, no use of drugs that induces steatosis (amidarone, methotrexate, systemic glucocorticoid, tetracycline, tamoxifen, estrogen, anabolic steroids, valporic acid)

Exclusion Criteria

those who are not interested in participating in the study, pharmacological treatment with some potential treatment, any diseases which need special treatment, pregnancy during the study period

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
AST enzyme. Timepoint: before & after intervention (after 12 weeks intervention. Method of measurement: enzymatic colorimetry kit.;ALT enzyme. Timepoint: before & after intervention (after 12 weeks intervention. Method of measurement: enzymatic colorimetry kit.;Hepatic fat infiltration status. Timepoint: before & after intervention (after 12 weeks intervention. Method of measurement: ultrasound.

Secondary Outcome Measures