A clinical trial to study the reduction in pain and redness of gums with additional use of Grapefruit seed and Pomegranate extract mouth rinse along with local application of steroids in patients with red, burning and ulcerated gums associated with Oral Lichen Planus.
Phase 4
- Conditions
- Health Condition 1: K137- Other and unspecified lesions of oral mucosa
- Registration Number
- CTRI/2024/07/071239
- Lead Sponsor
- Dr. Ankitha Miriya Alias
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Patients with clinical or histopathological diagnosis of Oral Lichen Planus (OLP) with desquamative gingivitis.
Exclusion Criteria
Patients already under topical or systemic corticosteroid medications for Oral Lichen Planus.
Patients with systemic diseases causing oral ulcerations like- gastrointestinal disorders.
Patients who are receiving or have received Chemotherapeutic drugs, Immunomodulators and topical or systemic Corticosteroids in the recent 1 year.
Pregnant and lactating mothers.
Patients with known allergy or contraindications to study medications.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Desquamative Gingivitis Clinical Score (0,1,2,3,4) to assess healing outcome of the lesion. <br/ ><br>2.Visual Analogue Scale (0 to 10)- to assess reduction in pain perceptionTimepoint: Baseline, 2 weeks post intervention, 4 weeks post intervention
- Secondary Outcome Measures
Name Time Method To evaluate the presence of side effects during the course of treatment.Timepoint: Baseline, 2 weeks post intervention, 4 weeks post intervention