Clinical Course of COVID-19 in Patients With Rheumatoid Arthritis Treated With or Without Hydroxychloroquine: a Case-control Study
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Severity of COVID-19 disease
研究概览
简要总结
evaluation of the clinical course of COVID-19 in a cohort of patients with rheumatoid arthritis treated with or without hydroxychloroquine.
详细描述
Study settings & sample:
This is an observational, retrospective -case-control, single-center study. This study will include patients who meet the inclusion criteria followed in the Department of Rheumatology and Rehabilitation, Tanta University Hospital, Tanta, Egypt.
Data will be taken from the medical records of patients with rheumatoid arthritis in the outpatient clinic of the Rheumatology and Rehabilitation Department, Tanta University Hospital, Tanta, Egypt. All patients will sign the informed consent form authorizing the collection of these data.
Group classification A) Patients with rheumatoid arthritis using hydroxychloroquine as a part of their treatment regimen.
b) Patients with rheumatoid arthritis not using hydroxychloroquine as a part of their treatment regimen.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients with rheumatoid arthritis superinfected with Covid-19
排除标准
- •Insufficient data are available in the medical record.
结局指标
主要结局
Severity of COVID-19 disease
时间窗: through study completion an average 12 weeks
WHO clinical management Covid19 interim guidance disease severity Algorithm
Length of hospitalization and ICU admission
时间窗: through study completion an average 12 weeks
Calculate the number of days that the patients stayed at the hospital and how many patients admitted to ICU
The need for mechanical ventilation
时间窗: through study completion an average 12 weeks
Calculate the number of patients who received mechanical ventilation
Number of patients in need for hospitalization
时间窗: through study completion an average 12 weeks
Estimate number of patients in need for hospitalization
次要结局
未报告次要终点
研究者
Mohammed Hassan Abu-Zaid
Principal Investigator
Tanta University