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Evaluation of a Food Supplement on Sleep Quality

Not Applicable
Completed
Conditions
Insomnia
Registration Number
NCT00484497
Lead Sponsor
Persee Medica
Brief Summary

The purpose of this study is to evaluate the efficacy on sleep quality of a food supplement.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
105
Inclusion Criteria
  • Healthy volunteer aged between 25 to 65 years
  • Patient diagnosed for primary Insomnia (threshold for inclusion: 10 on the ISI scale)
  • Healthy volunteer without diurnal sleep (total score for inclusion must be less than 10 on the Epworth scale)
  • Patient affiliated to the French Social Security
  • Patient who gave written informed consent
Exclusion Criteria
  • Secondary insomnia
  • History of severe psychiatric disorder, assessed by the MINI test
  • Resistance to Hypnotic drugs
  • Anxiety, depression, suicide, detected by the Beck Depression Inventory
  • Acute Pathology during the precedent three years
  • Breast feeding and pregnancy women
  • Non compliant volunteer
  • Hypersensibility to treatment composant

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Sleep quality assessed by the Leed Sleep Evaluation Questionnaire, measured after one month of treatment
Secondary Outcome Measures
NameTimeMethod
Sleep efficiency measured by ambulatory actigraphy (2 period)
Sleep quality assessed by the Leed Sleep Evaluation - Questionnaire, measured 15 days after treatment withdrawal
Sleep quality assessed by a Sleep diary completed each day during all the study period by the participants
Evolution of melatonin/6sulfatoxymelatonin ratio (before and after treatment)
Clinical General Impression of the clinician, before and after treatment.
Safety of the treatment (adverse event reporting)

Trial Locations

Locations (1)

Clinical Research Center- Hopital Cardiologique

🇫🇷

Lyon, France

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