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临床试验/NCT05004935
NCT05004935Unknown不适用

Analysis of Electromyography Activation Trunk Muscles and the Effect of Beetroot Juice Intake on the Results in Strength Exercises: Lateral Medicine Ball Throw and Sled Pushing

Poznan University of Physical Education2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2021年9月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
发起方
入组人数
20
试验地点
2
主要终点
The effect of beetroot juice consumption on plasma trimethylamine N-oxide concentration

研究概览

简要总结

The primary aim of the current study is to determine the effect of beetroot juice consumption on plasma trimethylamine N-oxide concentration.

A secondary aims: exploring the effect of circulating trimethylamine N-oxide modification on plasma total antioxidant status, and measurement of changes in the skin nicotinamide-adenine dinucleotide reduced form (NADH) content during transient ischemia and reperfusion.

详细描述

In a random order subjects will consume beetroot juice (140ml), or equimolar nitrates (NaNO3). Antecubital vein blood samples will be taken at the beginning, and every hour for 4 hours following consumption.

Plasma trimethylamine N-oxide, total antioxidant status, and nitrite/nitrate concentrations will be determined.

Using Flow Mediated Skin Fluorescence skin NADH content determined during controlled ischemia triggered by total occlusion of the brachial artery by the brachial blood pressure cuff and during reperfusion after deflation of the blood pressure cuff 2 and 4 hours following consumption.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Prevention
盲法
None

入排标准

年龄范围
18 Years 至 35 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • healthy volunteers

排除标准

  • 未提供

研究组 & 干预措施

nitrates

Active Comparator

single intake of 800mg nitrates (NaNO3)

干预措施: nitrate (Other)

结局指标

主要结局

The effect of beetroot juice consumption on plasma trimethylamine N-oxide concentration

时间窗: 4 hours

Determination of plasma trimethylamine N-oxide concentration following the beetroot juice consumption using ultra performance liquid chromatography - tandem mass spectrometer (UPLC-MS/MS) method.

次要结局

  • The effect of circulating trimethylamine N-oxide modification on plasma total antioxidant status(4 hours)

研究者

发起方
Poznan University of Physical Education
申办方类型
Other
责任方
Principal Investigator
主要研究者

Robert Olek

Principal Investigator

Poznan University of Physical Education

研究点 (2)

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