Neuromuscular Responses to Acute Beetroot Ingestion in Women Older Adults. Performance and Side Effects
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 9
- 试验地点
- 2
- 主要终点
- Changes in maximal isometric handgrip strength (N)
研究概览
简要总结
Beetroot juice supplementation has shown the capacity for provoking different physiological effects (e.g. vasodilation and muscle contraction increments). However, the effects of beetroot juice ingestion on neuromuscular performance in women older adults are barely studied. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance in women older adults
详细描述
Beetroot juice supplementation has shown the capacity for provoking different physiological effects that could affect human performance (e.g. vasodilation and muscle contraction increments). Although this dietary supplement has been commonly used for improving sports performance in recreational or professional athletes, the scientific literature in older adults is scarce. Thus, in our knowledge, no previous studies have analyzed the side effects associated to ingestion in this population group. In this randomized placebo-controlled study, we investigated the effects of beetroot acute supplementation in improving neuromuscular performance and side effects associated with ingestion in women older adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 80 Years（Older Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Women >65 or <85 years of age.
- •In good health, as determined by the investigator's review of history.
排除标准
- •(based in previous studies on this topic (doi: 10.1093/gerona/glaa311).
- •Men and women <65 or >85 years of age Unable to provide informed consent Current smokers Significant orthopedic limitations or other contraindications to strenuous exercise Those taking proton pump inhibitors, antacids, xanthine oxidase inhibitors, or on hormone replacement therapy Those taking anti-coagulants or on anti-platelet therapy History of neuromuscular disease (e.g., cervical spondylotic radiculomyelpathy, lumbar spondylosis, amyotrophic lateral sclerosis, Guillain-Barré syndrome, and acquired demyelinating polyneuropathies) Cardiovascular disease (e.g., > stage I hypertension, heart failure, myocardial infarction/ischemia significant myocardial or pericardial diseases (e.g. amyloidosis, constriction), Moderate or severe valvular disease, renal disease, liver disease, or anemia
结局指标
主要结局
Changes in maximal isometric handgrip strength (N)
时间窗: 1-week
Using a dynamometer and measuring dominant/ non-dominant side
Changes in Sit and Stand Test
时间窗: 1-week
Using Power Frail APP
Changes in Time Up and Go test
时间窗: 1-week
Using a photocell timing gates (seconds)
Changes in 6-m gait speed test
时间窗: 1-week
Using a photocell timing gates (seconds)
6-Minute Walk Test
时间窗: 1-week
次要结局
- Side effects questionnarie(1-week)
- Rate of perception effort (RPE)(1-week)
研究者
Álvaro López Samanés
PhD
Universidad Francisco de Vitoria