TO STUDY ROLE OF EPITHELIAL MESENCHYMAL TRANSITION MARKER IN ORAL CANCER
Not Applicable
- Conditions
- Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
- Registration Number
- CTRI/2021/08/035485
- Lead Sponsor
- AIIMS RISHIKESH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age â?? 18 to 70 years.
2.ECOG-PS 0-2.
3.Biopsy proved Oral cavity squamous cell carcinoma.
4.Treated with upfront surgery with curative intent.
5.Details of one-year regular follow-up available.
Exclusion Criteria
1.Recurrent cancer.
2.Synchronous / metachronous cancer.
3.Prior anticancer treatment (Surgery, chemotherapy, radiotherapy, immunotherapy).
4.Patient not willing to participate in the study.
5.Complete required information not available.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To estimate the Prevalence of expression of Epithelial Mesenchymal Transition markers E cadherin N cadherin Vimentin ZEB1 in oral cavity squamous cell cancersTimepoint: TWO YEARS JANUARY 01 2020 TO DECEMBER 31 2022
- Secondary Outcome Measures
Name Time Method 1.To study the correlation of Epithelial-Mesenchymal Transition markers expression with the disease stage and histopathological factors. <br/ ><br>2.To determine the role of Epithelial-Mesenchymal Transition markers expression in predicting 1-year locoregional control rates <br/ ><br>Timepoint: TWO YEARS JANUARY 01 2020 TO DECEMBER 31 2022