Hydrogen Sulfide Production by Oral Microflora
Completed
- Conditions
- Oral Malodor (Halitosis)
- Registration Number
- NCT00396539
- Lead Sponsor
- Hadassah Medical Organization
- Brief Summary
Oral malodor is a common condition. In most cases this condition results from the proteolytic activity of anaerobic oral bacteria. These bacteria produce volatile sulfide compounds which are fowl smelling and are felt during exhalation and speech. the aim of the present study is to examine a simple method of detecting these bacteria in samples taken from the oral cavity of oral malodor patients.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
- oral malodor patients
Exclusion Criteria
- smokers, users of antibiotic one month prior to study
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie hydrogen sulfide production by oral anaerobic bacteria in halitosis?
Are there comparative studies evaluating the efficacy of oral probiotics versus antimicrobial agents in reducing volatile sulfur compounds?
Which biomarkers correlate with hydrogen sulfide detection in oral malodor patients using microbiological assays?
What adverse events are associated with long-term suppression of oral hydrogen sulfide-producing bacteria?
How do combination therapies targeting oral biofilm and sulfur metabolism compare to monotherapies in halitosis management?
Trial Locations
- Locations (1)
Hadassah Medical Organization
🇮🇱Jerusalem, Israel
Hadassah Medical Organization🇮🇱Jerusalem, Israel