eg Muscle Metabolism Assessment in Critical Limb Ischemia with 7 Tesla MRI - CLI and 7T 31P MRS

niversitair Medisch Centrum Utrecht0 个研究点目标入组 30 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•- Age > 18 years;
•- Severe infra-popliteal PAOD (Fontaine class III and / or IV); Fontaine III: persistent, recurring rest pain requiring analgesia; Fontaine IV: non-healing ulcers present for > 4 weeks without evidence of improvement in response to conventional therapies
•- Ankle brachial index < 0.6 or unreliable (non-compressible or not in proportion to the Fontaine classification);
•- Written informed consent. ;The criteria apply to patients. Healthy controls may be included if they are above 18 years and have no signs of PAOD.

•-Pregnancy
•-Ineligible for scanning in the 7T MRI: subjects with cardiac pacemakers, claustrophobia, or metallic objects, i.e. stents, surgical clips etc. and all patients with bio-implants not explicitly indicated as safe to 7T MRI (see: mrisafety.com).;The abovementioned criteria apply to both patients and healthy controls.

发起方

niversitair Medisch Centrum Utrecht