NCT03230682Unknown不适用
Eealy Improvement Predicts Antidepressants Response in Adults With Major Depression Disorder
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- Early improvement
研究概览
简要总结
Early improvemrnt, decreased 20% in the 17 items of Hamilton Depression Rating Scale (HAMD-17) at the second week of the treatment of major depression disorder (MDD), can arguably predict the remission at the 12th week. Our observation study including 80 MDD patients will access resting-state function MRI to finding factors which infuencing early improvemrnt, respone and remission of antidepressants.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 16 Years 至 55 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •right-handed; HAMD-17 more than 17; diagnosed with MDD by the Structured Clinical Interview for DSM-IV
排除标准
- •patients diagnosed with other condition in DSM-IV Axis I; pregnency; Thyroid disease; Heart Disease
研究组 & 干预措施
major depressive disorder
干预措施: antidepressant (Drug)
结局指标
主要结局
Early improvement
时间窗: the second week of treatment
obtain 20% decrease of HAMD-17
次要结局
- Response(the 12th week of treatment)
研究者
Jianhui Fu
Department of Neurology, Huashan Hospital
Huashan Hospital
研究点 (1)
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