Budesonide/formoterol combination therapy versus budesonide plus tulobuterol-patch therapy in elderly asthmatic patients: A randomized, comparative study
- Conditions
- Bronchial Asthma
- Registration Number
- JPRN-UMIN000006551
- Lead Sponsor
- Second Department of Internal Medicine, Nagasaki University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 50
Not provided
1) Patients with a history of hypersensitivity(e.g contact dermatitis) to any ingredient contained in the budesonide/formoterol combination 2) Patients with a history of hypersensitivity to any ingredient contained in the tulobuterol-patch 3) Patients with infectious with no availabl effective antimicrobial drugs or with deep-seated mycosis 4) Patients with other respiratory illnesses(lung cancer, tuberculosis, bronchiectasis etc) 5) Patients with heart failure 6) Patients with RE 7) %FEV1<60% 8) Patients who contracted a respiratory infection that could influence asthma within the last 4 weeks 9) Patients who were treated with systemic corticosteroids in the last 4 weeks 10) Patients who are taking high-dose ICS 11) Patients who are taking PSL 12) Patients who are taking inhaled anticholinergic drugs 13) Patients who are treated with ZOREA(omalizumab) 14) Patients with other severe diseases 15) Patients who are considered inappropriate by the physician in charge
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement in the ACQ(asthma control questionnaire) score after 12 weeks
- Secondary Outcome Measures
Name Time Method Change of various indicator as follow 1)Fraction of exhaled Nitric Oxide 2)Lung function(FEV1.0 etc) 3)Asthma relevant QOL (miniAQLQ score) 4)Night-time awaking due to asthma 5)Symptom-free days