Improved effects of Budesonide/Formoterol combination therapy (Symbicort) on the residual eosinophilic inflammation in the distal airways of asthmatic patients who used the salmeterol/fluticasone combination drug
Not Applicable
- Conditions
- Bronchial asthma
- Registration Number
- JPRN-UMIN000003805
- Lead Sponsor
- JA Tohno Kousei Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Not provided
Exclusion Criteria
1. Past history of asthma attach in the previous 3 months. 2. Past treatments with oral corticosteroids in the previous 2 weeks. 3. Chronic obstructive lung disease (COPD) and other respiratory disease. 4. Severe liver, kidney, heart, hematic and other diseases 5. Inappropriate patients from the doctor's viewpoint
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method distal airway inflammation in induced sputum (Eosinophil counts, ECP and SPD)
- Secondary Outcome Measures
Name Time Method Asthma related QOL(AQLQ), impulse oscillometry system (IOS), FeNO, Pulmonary function test, Eosinophils in peripheral blood