Efficacy and Safety of DA-9401 on Improvement of Sperm Motility
- Conditions
- Spermatocele
- Interventions
- Dietary Supplement: DA-9401Dietary Supplement: Placebo
- Registration Number
- NCT03258437
- Lead Sponsor
- Korean Society for Sexual Medicine and Andrology
- Brief Summary
This study was conducted to investigate the effects of daily supplementation of Allium cepa L. and Cuscuta chinensis Lam. Extract Mixtures (DA-9401) on improvement of sperm motility.
- Detailed Description
This study was a 12 weeks, multi-center, randomized, double-blind, placebo-controlled human trial. Twenty subjects were randomly divided into Allium cepa L. and Cuscuta chinensis Lam. Extract Mixtures (DA-9401) or a placebo group. sperm motility profiles before and after the intervention.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 27
- Age 20-55 years
- sperm motility 40~69%
- History of alcohol or substance abuse
- Participation in any other clinical trials within past 1 months
- intense constipation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description DA-9401 DA-9401 capsules (4cap/d, 2.16 g/d) for 12 weeks. Placebo Placebo Placebo for 12 weeks.
- Primary Outcome Measures
Name Time Method Changes of Sperm motility 12 weeks Changes of sperm profile were assessed before and after the intervention
- Secondary Outcome Measures
Name Time Method Changes of Sperm count 12 weeks Changes of Sperm count(X10\^6(M)/ml) profile were assessed before and after the intervention
Changes of Ejaculated pH 12 weeks Changes of Ejaculated pH profile were assessed before and after the intervention
Changes of Sperm morphology 12 weeks Changes of Sperm morphology(%) profile were assessed before and after the intervention
Changes of MFS(Multidimensional Fatigue Scale) 12 weeks Changes of questionnaire profile were assessed before and after the intervention
Changes of Ejaculated volume 12 weeks Changes of Ejaculated volume(ml) profile were assessed before and after the intervention
Changes of hormone(Total testosterone, FSH, LH) 12 weeks Changes of hormone{Total testosterone(ng/ml), FSH and LH(mlU/ml)} profile were assessed before and after the intervention
Changes of IIEF(International Index of Erectile Function) 12 weeks Changes of questionnaire profile were assessed before and after the intervention
Trial Locations
- Locations (1)
Chonbuk National University Hospital of urology
🇰🇷Jeonju, Jeollabuk-do, Korea, Republic of