Efficacy of Enamel Matrix Derivative/ Freeze-Dried Bone Allograft VS Enamel Matrix Derivative/ Demineralized Freeze-Dried Bone Allograft with or without Forced Eruption Treating Infrabony Defects: Two Randomized Trials
Not Applicable
- Conditions
- Chronoc periodontitis
- Registration Number
- JPRN-jRCT1090220077
- Lead Sponsor
- Dr Shigeki Ogihara
- Brief Summary
Both FDBA and DFDBA graft materials worked well in the managing of deep infrabony defects when combined with EMD. This study showed that both forced eruption/EMD/FDBA and forced eruption/EMD/DFDBA combination therapies result in greater soft tissue improvements at 1- and 3- year follow-up in addition to greater hard tissue improvements at 6- months re-entry compared than forced eruption/EMD alone
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- OTHER
- Sex
- All
- Target Recruitment
- 69
Inclusion Criteria
6mm>CAL and radiographic bone loss
Exclusion Criteria
1) systematic diseases influencing periodontal surgery; 2) systematic medications affecting periodontal status; 3) pregnancy or lactation; 4) smoker; 5) sensitivity to minocycline and tetracycline.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The primary outcome measurewas absolute change in PD reduction and CAL gain from baseline to 1-year and 3 years follow-up.
- Secondary Outcome Measures
Name Time Method OPAL gain from baseline to 6 month