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Clinical application of autogenous demineralized dentin matrix prepared immediately after extraction for alveolar bone regeneratio

Not Applicable
Conditions
ost of alveolar bone
Registration Number
JPRN-UMIN000041510
Lead Sponsor
Department of Regenerative Oral Surgery, Unit of Translational Medicine, Nagasaki University Graduate School of Biomedical Sciences
Brief Summary

The clinical application of APDDM prepared immediately after tooth extraction to bone augmentation, taking advantage of the relatively short preparation time due to partial demineralization. APDDM, as introduced in this study, is an efficient, safe, and reasonable bone substitute. Consequently, this material has the potential to become one of the options as a bone substitute in implant dentistry.

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete: follow-up complete
Sex
All
Target Recruitment
40
Inclusion Criteria

Not provided

Exclusion Criteria

a) Patients who had undergone radiation therapy in the oral and maxillofacial region,b) Patients who had undergone other bone grafting in the surgical area, and who had the history of maxillary sinus disease or symptoms were excluded. c) Patients who had uncontrolled systemic disease were also excluded.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
After implantation of the ADDM at 4, 8, 16, and/or 24 weeks, we evaluated the tissue with histology and radiology.
Secondary Outcome Measures
NameTimeMethod
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