Lung Recruitment and Postoperative CPAP in Pediatric Laparoscopic Surgery
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Anesthesia
- Sponsor
- Assiut University
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- (A-a) DO2
- Status
- Completed
- Last Updated
- 9 years ago
Overview
Brief Summary
General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation.
Detailed Description
General anesthesia lowers FRC thereby promoting airway closure and absorption atelectasis. Alveolar recruitment manoeuvers recruit collapsed alveoli, increase gas exchange, and improve arterial oxygenation. However, the effect of recruitment manoeuvre is short lasting and does not extend to the post operative period. Postoperative CPAP keeps the lung open and can improve oxygenation in the early postoperative period.
Investigators
Hala Saad Abdel-Ghaffar
MD
Assiut University
Eligibility Criteria
Inclusion Criteria
- •Pediatric patients undergoing laparoscopic surgery for abdominal cryptorchidism.
Exclusion Criteria
- •Cardio-respiratory illness.
- •Unsatisfactory preoperative peripheral arterial oxygen saturation.
- •Unsatisfactory preoperative hemoglobin level.
- •Neurological or psychiatric disease.
- •Children with a BMI \>95th percentile for age.
Outcomes
Primary Outcomes
(A-a) DO2
Time Frame: 1 hour after extubation
arterial blood gas will be withdrawn 1 hour after extubation and the alveolar minus arterial oxygen difference will be calculated for assessment of oxygenation
Secondary Outcomes
- PaCO2(intra-operative and 1hour postoperative)
- PaO2(intra-operative and 1hour postoperative)
- PH(intra-operative and 1hour postoperative)
- Respiratory mechanics(Intraoperative)
- non invasive mean arterial pressure(intraoperative and 1hour postoperative)
- Heart rate(intraoperative and 1hour postoperative)
- Peripheral arterial oxygenation SPO2%(intraoperative and 1hour postoperative)