Handling Medium for ICSI With Ionomycin and Latrunculin A

Not Applicable

Completed

• Conditions: Infertility
• Interventions: Other: Doing ICSI I a medium supplemented with Ionomycin and Latrunculin A

• Registration Number: NCT03678610
• Lead Sponsor: Ibn Sina Hospital

Brief Summary

Using Latrunculin A and Ionomycin would improve the outcome of ICSI if the handling medium during the ICSI procedure has them.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2018-09-17
• Study First Submitted QC: 2018-09-18
• Study First Posted: 2018-09-19
• Study Start: 2018-09-25
• Status Verified: 2019-05
• Primary Completion: 2019-05-01
• Study Completion: 2019-05-01
• Last Update Submitted: 2019-05-05
• Last Update Posted: 2019-05-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 700

Inclusion Criteria

• indication for ICSI

Exclusion Criteria

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
ICSI medium supplemented with Ionomycin and Latrunculin A	Doing ICSI I a medium supplemented with Ionomycin and Latrunculin A	-

Primary Outcome Measures

Name	Time	Method
Fertilization rate	6 days of culture

Secondary Outcome Measures

Name	Time	Method
clinical pregnancy rate	three months
Rates of Blastocyst formation and quality	6 days of culture	Number of formed blastocysts and blastocysts with good-quality per fertilized oocytes
embryo utilization rate	6 days of culture
ongoing pregnancy rate	12 weeks

Trial Locations

Locations (3)

IbnSina IVF Center; 🇪🇬 Sohag, Egypt

Banon Assiut; 🇪🇬 Assiut, Egypt

Qena Fertility Center; 🇪🇬 Qena, Egypt