MedPath

Comparison of Erector Spinae Plane Block and Intravenous Analgesic in Nefrectomy

Not Applicable
Completed
Conditions
Regional Anesthesia Morbidity
Nephrectomy
Interventions
Procedure: erector spinea plane block administered preoperative open nephrectomy
Procedure: intravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kg
Registration Number
NCT04686890
Lead Sponsor
Kocaeli University
Brief Summary

The efficacy of erector spinae plane block versus intravenous analgesics compared relate to the morphine consumptions

Detailed Description

Patients undergoing elective nefrectomy were enrolled. Patients divided into two groups with a sealed envelope technique to ESP+ pca morphine group or iv analgesic + pca morphine group. All patients will premedicated. then esp will applied to one group before surgery at the preoperative care unit by the same anesthesiologist. The other group will receive intravenous tramadol 1 mg/kg + NSAID 1 ampule + parol 10 mg/ kg + ondansetron 4 mg bolus. İntravenous morphine pca with a concentration of 0.5 mg/cc were applied. And administered 1 mg boluses every 15 minutes lock time and 4 hour limit as 4 mg arranged. An anesthesia nurse who is responsible of all pcas' in the hospital was recorded the variables of these patients in the service

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
46
Inclusion Criteria

18-65 years age

  • ASA I-II
  • undergoing elective nephrectomy
Exclusion Criteria
  • ASA>3
  • heart disease
  • pregnancy
  • lung disease
  • scoliosis
  • bleeding disorder
  • infection at the manipulation side

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
postoperative opiod (morphine) consumptionerector spinea plane block administered preoperative open nephrectomypatient-controlled analgesia (15 minutes. lock time, 2 ml bolus= total 1 mg morphine intravenously, limited to maximum 4 bolus / per hour )
postoperative numerated rating scaleerector spinea plane block administered preoperative open nephrectomyat the 1, 3, 6, 12 and 24 th hour postoperatively - numerated rating scale score was evaluated and recoded as 0= no pain (better), 10: unbearable pain (worse)
postoperative numerated rating scaleintravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kgat the 1, 3, 6, 12 and 24 th hour postoperatively - numerated rating scale score was evaluated and recoded as 0= no pain (better), 10: unbearable pain (worse)
postoperative opiod (morphine) consumptionintravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kgpatient-controlled analgesia (15 minutes. lock time, 2 ml bolus= total 1 mg morphine intravenously, limited to maximum 4 bolus / per hour )
peroperative continuous opioid (remifentanil) consumptionerector spinea plane block administered preoperative open nephrectomycontinuous remifentanil infusion was given during the whole procedure
peroperative continuous opioid (remifentanil) consumptionintravenous analgesic ( 1 mg/kg tramadol + non-steroid antiinflamatuar paracetamol )drug + 10 mg.kgcontinuous remifentanil infusion was given during the whole procedure
Primary Outcome Measures
NameTimeMethod
Postoperative intravenous morphine patient controlled analgesia consumptionduring postoperatively

morphine consumptions were recorded till 24 th hour postoperatively

Peroperative remifentanyl consumptionPeroperatively

Amount of Remifentanyl consumption recorded

Secondary Outcome Measures
NameTimeMethod
Visual analog rating scoresduring postoperative surgery

pain scores were recorded during surgery

Trial Locations

Locations (1)

Kocaeli University Medical Faculty

🇹🇷

Kocaeli, Turkey

© Copyright 2025. All Rights Reserved by MedPath