Stents, Drug Eluting Stents, and CABG- Financial and Clinical Impact.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 700
研究概览
简要总结
Options for coronary revascularization include stent implantation and coronary bypass surgery. Both modalities have their unique advantages and disadvantages in terms of clinical outcomes as well as financial impact on the medical system. We wish to investigate the late results of patients undergoing coronary revascularization, the need for re-hospitalization, re-intervention, patient satisfaction as well as the financial burden on the medical system. The study will be conducted by historical prospective review of hospital records in conjunction with records of the medical insurance companies ("HMO's").
详细描述
Cardio-vascular disease is the second leading cause of death in the western world. Two modes of treatment are currently used:
Coronary Artery Bypass Graft (CABG) Percutaneous Interventions (PCIs) i.e: balloon angioplasty and stents[ bare metal (BMS) and drug eluting (DES)].
CABG is a major operation but is considered to be safe and with good quality of life in the years to follow. The initial cost of CABG is high but usually stays low thereafter.
PCI is less invasive but its downfall is a high rate of restenosis hence leading to the return of angina. The initial cost is low but due to the return of symptoms the cost increases.
The goal of DES is to lower the rate of restenosis thus reducing the need for repeat hospitalizations and procedures. The initial cost of this stent is higher than that of the BMS but still lower than that of CABG.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients which are insured in the relevant HMO's and suffer from a multi-vessel coronary disease with occlusion of at least 70% of at least two of the main coronary vessels.
排除标准
- •Non multi- vessel Disease
- •Any additional cardiac disease
- •Low EF (<30%)
- •Liver disease - according to liver enzymes
- •Other cardiac treatment (past or immediate future)
- •Active MI (24hrs before revascularization)
- •Previous revascularization before beginning of follow up.