A comparative evaluation of oxygen releasing formula and chlorhexidine gel as an adjunct to scaling and root planing in the management of patients with stage II grade A periodontitis. A clinico microbiology study.
试验速览
- 阶段
- 3 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
- 试验地点
- 1
研究概览
简要总结
This study evaluates the comparative efficacy of the commercially available oxygen releasing gel and chlorhexidine gel as local drug delivery agents in patients with Stage II Grade A periodontitis. The oxygen releasing gel exerts its antimicrobial effect by releasing active oxygen into the periodontal pocket, creating an unfavorable environment for anaerobic periodontal pathogens and supports wound healing, while chlorhexidine gel acts as a broad spectrum antimicrobial with proven substantivity against periodontal microorganisms. Clinical parameters like gingival index, modified sulcus bleeding index, probing pocket depth and clinical attachment level will be analysed along with micro biological analysis of colony forming units of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans at baseline that is 0th day and 30 days post treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- None
入排标准
- 年龄范围
- 30.00 Year(s) 至 55.00 Year(s)（—）
- 性别
- All
入选标准
- •Subjects with Stage II grade A periodontitis.
- •Probing pocket depth less than or equal to 5mm, with minimal bone loss in the past five years.
- •Subjects with a minimum of 20 teeth and at least two periodontal pockets.
- •Subjects with clinical attachment loss of 3 to 4mm.
排除标准
- •Prior or current antibiotic therapy.
- •Medication inducing gingival enlargement.
- •Pregnant or lactating women.
- •Subjects with the habit of tobacco chewing and smoking.
- •Immunocompromised subjects.
研究者
Haripriya H R
Sri Hasanamba dental college and hospital