Investigating the effect of dexmedetomidine drug administration on hemodynamic changes and sedation after heart surgery in opium addicted patients

Phase 3

Recruiting

• Conditions: F11.1; Condition 1: Coronary artery bypass surgery. Condition 2: addiction to opiod.; Atherosclerotic cardiovascular disease, so described; Opioid abuse; I25.0

• Registration Number: IRCT20230825059256N1
• Lead Sponsor: Kerman University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 16 October 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 112

Inclusion Criteria

Drug addiction (opium, methadone and syrup) based on DSM-V criteria
Patients undergoing on-pump heart surgery
Stable hemodynamics
Patients without cardiac pacemaker
Absence of liver and kidney disorders
Patients willing to participate in the study

Exclusion Criteria

Bradycardia with a rate less than 60 beats per minute
Unstable hemodynamics
People who need high-dose vasoconstrictor drugs
profuse bleeding
Disagreement to continue cooperation in the study by the first degree companions

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Hemodynamic changes. Timepoint: At the beginning, 3, 6, 8 and 12 hours after the operation. Method of measurement: Monitoring device.;Relaxation. Timepoint: At the beginning, 3, 6, 8 and 12 hours after the operation. Method of measurement: modified Ramsay scores.