Developing an intervention to improve paediatric HIV care in central Mozambique

Not Applicable

Completed

• Conditions: HIV disease; Infections and Infestations; Human immunodeficiency virus [HIV] disease

• Registration Number: ISRCTN67747315
• Lead Sponsor: Centro de Investigação Operacional Da Beira

Brief Summary

2020 results in https://pubmed.ncbi.nlm.nih.gov/32183779/ (added 10/11/2020)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Completion: 2017-02-20
• Study Start: 2019-07-25
• Last Update Posted: 24 November 2020

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

Clinics:
1. High patient volume in antenatal care (ANC).
2. High HIV prevalence in ANC.
3. Already implementing Option B+ (HIV test and treat for pregnant mothers).
4. Located along the Beira highway corridor to assure access.

Health workers:
1. Providers of post-partum, child-at-risk, and ART services at each clinic.

Mothers:
1. Active women members of HIV-positive members at each clinic site.
2. HIV-positive Women, age 18-44.
3. Patient at a local clinic.

Exclusion Criteria

N/A

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<br> Data on all outcomes are gathered at 3-month intervals at each of the six clinics, beginning at baseline (3 months before the intervention began):<br> 1. PCR testing rates among HIV-exposed infants presenting to CCR.<br> 2. The proportion of HIV-exposed infants attending 2 or more CCR visits.<br> 3. The proportion of HIV-exposed infants at CCR receiving cotrimoxazole prophylaxis.<br> 4. The proportion of HIV-positive infants identified via PCR at CCR clinics who enrol in care at an HIV treatment clinic within 45 days of positive test results (known as consulta de TARV, or ART).<br>

Secondary Outcome Measures

Name	Time	Method
<br> Data on all outcomes are gathered at 3-month intervals at each of the six clinics, beginning at baseline (3 months before the intervention began):<br> 1. The proportion of caregivers of infants with positive PCR result who are notified of infant’s positive HIV status.<br> 2. The time interval from CCR visit at which PCR test sample obtained to first ART visit for PCR positive infants.<br> 3. The acceptability of EID oriented intervention to healthcare workers and HIV-positive mothers measured using individual interviews, focus group discussions to the mothers and routine data collections.<br>